A part of MilliporeSigma

MABE516 | Anti-ADAR, clone EPR7034, Rabbit Monoclonal Antibody

100 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, IHC Rb Unpurified Monoclonal Antibody
      Catalogue NumberMABE516
      DescriptionAnti-ADAR, clone EPR7034, Rabbit Monoclonal Antibody
      Alternate Names
      • Double-stranded RNA-specific adenosine deaminase
      • DRADA
      • 136 kDa double-stranded RNA-binding protein
      • p136
      • Interferon-inducible protein 4
      • IFI-4
      • K88DSRBP
      Background InformationADAR, also named Double-stranded RNA-specific adenosine deaminase (DRADA) or 136 kDa double-stranded RNA-binding protein (p136), Interferon-inducible protein 4 (IFI-4), or K88DSRBP and encoded by the genes ADAR1, DSRAD, G1P1, IFI4 is an enzyme involved in RNA editing and catalyzes the deamination of adenosine to inosine in ds(RNA). Such editing influences RNA expression in numerous ways from translation , to splicing, to genetic stability and can even be used in viral defense and RNA replication mechanisms. ADAR cellular RNA substrates include bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2) and serotonin (HTR2C) and GABA receptor (GABRA3). Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alters their functional activities. ADAR is found localized in the nucleus and cytoplasm and widely expressed particularly in the brain and lung.
      Product Information
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      ApplicationPlease note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50-100 dilution from a representative lot detected ADAR in human brain tissue.

      Produced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human ADAR.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • ADAR
      • ADAR1
      • DSRAD
      • G1P1
      • IFI4
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~120 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa, HepG2, and K562 cell lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected ADAR in HeLa, HepG2, and K562 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information