116801 | Adenosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 37839-81-9 - Calbiochem

116801
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₀H₁₁N₅O₆P · Na 37839-81-9

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      116801-100MG
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          Glass bottle 100 mg
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          116801-1GM
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              Plastic ampoule 1 gm
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              Description
              OverviewA key regulator of many cellular reactions. Released in response to hormonal stimulation. An activator of protein kinase A. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.
              Catalogue Number116801
              Brand Family Calbiochem®
              SynonymsA-3:5-MP, cAMP, Na
              References
              ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
              de Rooij, J., et al. 1998. Nature 396, 474.
              Lomo, J., et al. 1995. J. Immunol. 154, 1634.
              Product Information
              CAS number37839-81-9
              ATP CompetitiveN
              FormWhite solid
              Hill FormulaC₁₀H₁₁N₅O₆P · Na
              Chemical formulaC₁₀H₁₁N₅O₆P · Na
              Hygroscopic Hygroscopic
              ReversibleN
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Primary TargetProtein kinase A
              Purity≥98% by HPLC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSAU7357900
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              116801

              References

              Reference overview
              Kawasaki, H., et al. 1998. Science 282, 2275.
              de Rooij, J., et al. 1998. Nature 396, 474.
              Lomo, J., et al. 1995. J. Immunol. 154, 1634.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision07-April-2008 RFH
              SynonymsA-3:5-MP, cAMP, Na
              DescriptionA key regulator of many cellular reactions. Second messenger molecule released in response to hormonal stimulation. An activator of protein kinase A. Induces the guanine-nucleotide-exchange factor activity of GEFI, also known as Epac (exchange protein directly activated by cAMP), and GEFII towards Rap1 both in vitro and in vivo. Promotes apoptosis in resting human B lymphocytes.
              FormWhite solid
              CAS number37839-81-9
              RTECSAU7357900
              Chemical formulaC₁₀H₁₁N₅O₆P · Na
              Structure formulaStructure formula
              Purity≥98% by HPLC
              SolubilityH₂O (10 mg/ml)
              Storage -20°C
              Hygroscopic
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
              Toxicity Standard Handling
              Merck USA index14, 2708
              ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
              de Rooij, J., et al. 1998. Nature 396, 474.
              Lomo, J., et al. 1995. J. Immunol. 154, 1634.