104550 | ACA - CAS 110683-10-8 - Calbiochem

104550
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₁H₂₃NO₃ 110683-10-8

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      104550-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewA cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets. Inhibits ATP-stimulated phosphatidylcholine (PC) secretion in alveolar type II cells. Also blocks phorbol ester and A23187-induced PC secretion in type II cells. Reported to block glucose-induced insulin secretion by pancreatic β-cells. Exhibits moderate leukotriene antagonist activity.
          Catalogue Number104550
          Brand Family Calbiochem®
          SynonymsN-(p-Amylcinnamoyl)anthranilic Acid
          References
          ReferencesLiu, L., et al. 1999. J. Cell. Biochem. 72, 103.
          Simonsson, E., et al. 1998. Diabetes 47, 1436.
          Konrad, R.J., et al. 1992. Biochim. Biophys. Acta 1135, 215.
          Banga, H.S., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 9197.
          Product Information
          CAS number110683-10-8
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₂₁H₂₃NO₃
          Chemical formulaC₂₁H₂₃NO₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetA2PLA2
          Purity≥99% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          104550

          References

          Reference overview
          Liu, L., et al. 1999. J. Cell. Biochem. 72, 103.
          Simonsson, E., et al. 1998. Diabetes 47, 1436.
          Konrad, R.J., et al. 1992. Biochim. Biophys. Acta 1135, 215.
          Banga, H.S., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 9197.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-August-2016 JSW
          SynonymsN-(p-Amylcinnamoyl)anthranilic Acid
          DescriptionInhibits epinephrine-stimulated thromboxane production (86% at 3.5 μM) via inhibition of phospholipase A2 (PLA2) in human platelets. Also blocks glucose-induced insulin secretion in pancreatic islets. Possesses moderate leukotriene antagonist activity.
          FormWhite solid
          CAS number110683-10-8
          Chemical formulaC₂₁H₂₃NO₃
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityEthanol (10 mg/ml) or DMSO (50 mg/ml)
          Storage +15°C to +30°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesLiu, L., et al. 1999. J. Cell. Biochem. 72, 103.
          Simonsson, E., et al. 1998. Diabetes 47, 1436.
          Konrad, R.J., et al. 1992. Biochim. Biophys. Acta 1135, 215.
          Banga, H.S., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 9197.