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343922 | 5-Fluorouracil - CAS 51-21-8 - Calbiochem

343922
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄H₃FN₂O₂ 51-21-8

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      343922-1GM
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          Glass bottle 1 gm
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          Description
          OverviewPotent antitumor agent. Inhibits aminoisobutyrate-pyruvate aminotransferase. Induces apoptosis in human colon cancer cell lines.
          Catalogue Number343922
          Brand Family Calbiochem®
          Synonyms5-FU
          References
          ReferencesPressacco, J., et al. 1996. Br. J. Cancer 72, 939.
          Shchepotin, I.B., et al. 1994. Anticancer Res. 14, 1027.
          Product Information
          CAS number51-21-8
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₄H₃FN₂O₂
          Chemical formulaC₄H₃FN₂O₂
          ReversibleN
          Structure formula Image
          Applications
          Biological Information
          Primary TargetAminoisobutyrate-pyruvate aminotransferase
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSYR0350000
          Safety Information
          R PhraseR: 21/22

          Harmful in contact with skin and if swallowed.
          S PhraseS: 36/37

          Wear suitable protective clothing and gloves.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          343922

          References

          Reference overview
          Pressacco, J., et al. 1996. Br. J. Cancer 72, 939.
          Shchepotin, I.B., et al. 1994. Anticancer Res. 14, 1027.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-May-2008 RFH
          Synonyms5-FU
          DescriptionPotent antitumor agent that inhibits aminoisobutyrate-pyruvate aminotransferase. Induces apoptosis of human colon cancer cell lines.
          FormWhite solid
          CAS number51-21-8
          RTECSYR0350000
          Chemical formulaC₄H₃FN₂O₂
          Structure formula
          Purity≥98% by HPLC
          SolubilityDMF (5 mg/ml), DMSO (5 mg/ml), Methanol (1 mg/ml), or hot H₂O (1 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          Merck USA index14, 4181
          ReferencesPressacco, J., et al. 1996. Br. J. Cancer 72, 939.
          Shchepotin, I.B., et al. 1994. Anticancer Res. 14, 1027.