505771 | 4-DAMP - CAS 1952-15-4 - Calbiochem

505771
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₁H₂₆INO₂ 1952-15-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05771.0001
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          Glass bottle 25 mg
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          Description
          OverviewAn antagonist selective for mAChRs (Ki = 0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively). Used frequently in investigating the functional roles of M1 and M3 receptors in both central and peripheral nervous systems.
          Catalogue Number505771
          Brand Family Calbiochem®
          Synonyms1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP
          References
          ReferencesKruse, C., et al., 2012. Nature. 482, 552.
          Moriya, H., et al., 1999. Life Sci. 64, 2351.
          Ehlert, J., 1996. Life Sci. 58, 1971.
          Product Information
          CAS number1952-15-4
          FormWhite solid
          Hill FormulaC₂₁H₂₆INO₂
          Chemical formulaC₂₁H₂₆INO₂
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetMuscarinic Receptors
          Primary Target K<sub>i</sub>0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Kruse, C., et al., 2012. Nature. 482, 552.
          Moriya, H., et al., 1999. Life Sci. 64, 2351.
          Ehlert, J., 1996. Life Sci. 58, 1971.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          Synonyms1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP
          DescriptionAn antagonist selective for mAChRs (Ki = 0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively). Used frequently in investigating the functional roles of M1 and M3 receptors in both central and peripheral nervous systems.
          FormWhite solid
          CAS number1952-15-4
          Chemical formulaC₂₁H₂₆INO₂
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO (100 mM) or Ethanol (25 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesKruse, C., et al., 2012. Nature. 482, 552.
          Moriya, H., et al., 1999. Life Sci. 64, 2351.
          Ehlert, J., 1996. Life Sci. 58, 1971.