112251 | α₁-Acid Glycoprotein, Human Plasma

112251
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      112251-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewNative α1-acid glycoprotein from human plasma. Glycoprotein used for the study of the structure of oligosaccharide units. Consists of 40 - 45% carbohydrate. Present in human plasma at concentrations of 55 - 140 mg/100 ml. Clinically, α1-AG is an acute-phase reactant that, together with haptoglobin, indicates acute inflammation. Selectively suppresses the augmentation of NK cell activity by IFN-α and IFN-γ. The α1-AG:α1-antitrypsin ratio is useful in diagnosis of liver disease. A sialic acid-deficient α1-AG has been observed in serum or urine of patients with Hodgkin’s disease, psoriatic arthritis, diabetes, and chronic myeloid leukemia. Sialic acid-deficient α1-AG has an affinity for vitamin B12.
          Catalogue Number112251
          Brand Family Calbiochem®
          Synonymsα₁-AG, C-AGP, Orosomucoid, α₁M-Seromucoid
          References
          ReferencesAso, H., et al. 1999. Inflammation 23, 117.
          Schmid, K., et al. 1973. Biochemistry 12, 2711.
          Product Information
          CAS number66455-27-4
          FormLyophilized
          Applications
          Biological Information
          Purity≥95% by SDS-PAGE
          SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for to 3 months at (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          112251

          References

          Reference overview
          Aso, H., et al. 1999. Inflammation 23, 117.
          Schmid, K., et al. 1973. Biochemistry 12, 2711.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-December-2011 JSW
          Synonymsα₁-AG, C-AGP, Orosomucoid, α₁M-Seromucoid
          DescriptionNative α1-acid glycoprotein from human plasma. Glycoprotein used for the study of the structure of oligosaccharide units. Consists of 40-45% carbohydrate. Present in human plasma at concentrations of 55-140 mg/100 ml. Clinically, α1-AG is an acute phase reactant that, together with haptoglobin, indicates acute inflammation. Selectively suppresses the augmentation of NK cell activity by IFN-α and IFN-γ. The α1-AG:α1-antitrypsin ratio is useful in diagnosis of liver disease. A sialic acid-deficient α1-AG has been observed in serum or urine of patients with Hodgkin's disease, psoriatic arthritis, diabetes, and chronic myeloid leukemia. Sialic acid-deficient α1-AG has an affinity for vitamin B12.
          FormLyophilized
          SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          CAS number66455-27-4
          Purity≥95% by SDS-PAGE
          SolubilityAqueous buffers (1 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for to 3 months at (-20°C).
          Toxicity Standard Handling
          ReferencesAso, H., et al. 1999. Inflammation 23, 117.
          Schmid, K., et al. 1973. Biochemistry 12, 2711.