505982 | (-)-Quinpirole Hydrochloride - CAS 85798-08-9 - Calbiochem

505982
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₃H₂₁N₃•HCl 85798-08-9

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05982.0001
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          Glass bottle 10 mg
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          Description
          OverviewA potent, selective dopamine D2 receptor agonist with a Ki value of 4.8 nM. Some D3(Ki = 24 nM) and D4 (Ki = 30 nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5 nM).
          Catalogue Number505982
          Brand Family Calbiochem®
          SynonymsDopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555
          References
          ReferencesOʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
          Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
          Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.
          Product Information
          CAS number85798-08-9
          FormWhite powder
          Hill FormulaC₁₃H₂₁N₃•HCl
          Chemical formulaC₁₃H₂₁N₃•HCl
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetD₂
          Primary Target K<sub>i</sub>4.8 nM
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          OʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
          Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
          Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          SynonymsDopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555
          DescriptionA potent, selective dopamine D2 receptor agonist with a Ki value of 4.8 nM. Some D3(Ki = 24 nM) and D4 (Ki = 30 nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5 nM).
          FormWhite powder
          CAS number85798-08-9
          Chemical formulaC₁₃H₂₁N₃•HCl
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (7.3 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesOʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
          Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
          Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.