505897 | (±)-PD 128907 Hydrochloride - CAS 112960-16-4 - Calbiochem

505897
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₄H₁₉NO₃•HCl 112960-16-4

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05897.0001
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          Glass bottle 5 mg
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          Description
          OverviewSelective dopamine D3 receptor agonist (Ki = 2.3 nM) with an 18-fold selectivity over long dopamine receptors (D2L) and exhibited only weak affinity for D4.2 receptors (Ki = 169 nM). Commonly used to reproduce cocaine′s discriminative stimulus effects and also in peripheral systemic studies of hypertension.
          Catalogue Number505897
          Brand Family Calbiochem®
          SynonymsDopamine D₃ Receptor Agonist, PD 128,907, PD 128907, PD128907
          References
          ReferencesAchat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther. 334, 556.
          Zeng, C. et al. 2006. Circul. Res. 99, 494.
          Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther. 275, 1355.
          Product Information
          CAS number112960-16-4
          FormWhite powder
          Hill FormulaC₁₄H₁₉NO₃•HCl
          Chemical formulaC₁₄H₁₉NO₃•HCl
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetD₃
          Primary Target K<sub>i</sub>2.3 nM
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Achat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther. 334, 556.
          Zeng, C. et al. 2006. Circul. Res. 99, 494.
          Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther. 275, 1355.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-September-2013 JSW
          SynonymsDopamine D₃ Receptor Agonist, PD 128,907, PD 128907, PD128907
          DescriptionSelective dopamine D3 receptor agonist (Ki = 2.3 nM) with an 18-fold selectivity over long dopamine receptors (D2L) and exhibited only weak affinity for D4.2 receptors (Ki = 169 nM). Commonly used to reproduce cocaine′s discriminative stimulus effects and also in peripheral systemic studies of hypertension.
          FormWhite powder
          CAS number112960-16-4
          Chemical formulaC₁₄H₁₉NO₃•HCl
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (5 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesAchat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther. 334, 556.
          Zeng, C. et al. 2006. Circul. Res. 99, 494.
          Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther. 275, 1355.