Discovery & Development
Lead Discovery Kinases & Phosphatases


Phosphate groups are post-translational modifications that regulate many disease states, including cancer, neurodegenerative diseases, diabetes, pain, autoimmunity, and cardiovascular diseases. As a result, the responsible modifying enzymes – kinases and phosphatases – have been a focus of therapeutic modulation, with the hopes of improving human health.
Products for Kinase Drug Discovery
  • Upstate® Kinases and Phosphatases: catalog and bulk quantities validated for high-throughput screening
  • HTRF® Lipid Kinase Assay Kits for research and high-throughput screening
  • Calbiochem® Inhibitors and Substrates