Flow Cytometry Applications - Cell Biology
General cell biology is rapidly expanding its use of flow cytometry as a tool to examine pathways and propose biologically-relevant mechanisms of action in pathologies such as cancer. As shown below, many new applications are currently available to aid research in this area.
Signal transduction pathways lead to diverse outcomes, such as apoptosis, cell differentiation, cell growth and cell proliferation, all of which have been extensively studied in the process of developing therapies for various cancers and autoimmune disease. Cross-talk among signaling pathways adds an extra dimension of complexity when analyzing physiological consequences of a pathway of interest. However, there are some key nodes at which multiple signals are integrated. Multiparametric flow cytometry provides researchers the power to monitor these key intracellular ‘checkpoints’ simultaneously, enabling analysis of complicated cell events.
Download our application note on cell signaling HERE.
Amnis® systems are ideal for a variety of applications in oncology involving characterization of tumors.
New customized instrument formats allow green and red fluorescent protein detection on the easyCyte™ system. Amnis® systems also have the ability to detect a variety of fluorescent proteins.HERE.