Pyrogen contamination in pharmaceutical products, biotherapeutics and medical devices can induce life-threatening fever. Pyrogen detection is therefore of major importance with regard to patient safety. The detection of pyrogens in parenteral products can now be performed without using animal-based tests.
With the latest European regulations in place, you can now switch to the new Monocyte-Activation Test (MAT). Currently the best alternative to animal-based testing methods enabling the detection of the full range of pyrogens to ensure patient safety. The MAT is an in vitro test that mimics the human reaction to pyrogens.
With MilliporeSigma you can benefit from our expertise in MAT while ensuring compliance with the latest regulations. We offer ready-to-use kits for an easy-to-perform pyrogen test in your own lab.