584222 Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

584222
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₉H₁₆N₂O₆ 18771-50-1

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      584222-10MG
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          Plastic ampoule 10 mg
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          Description
          OverviewPotent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O(Cat. No. 584223).
          Catalogue Number584222
          Brand Family Calbiochem®
          References
          ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
          Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
          Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
          Riva, C., et al. 1992. Chemotherapy 38, 358.
          Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
          Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
          Product Information
          CAS number18771-50-1
          FormWhite to off-white solid
          Hill FormulaC₉H₁₆N₂O₆
          Chemical formulaC₉H₁₆N₂O₆
          Hygroscopic Hygroscopic
          Applications
          Biological Information
          Purity≥90% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSUW5798980
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Tetrahydrouridine - CAS 18771-50-1 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Tetrahydrouridine - CAS 18771-50-1 - Calbiochem Certificates of Analysis

          TitleLot Number
          584222

          References

          Reference overview
          Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
          Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
          Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
          Riva, C., et al. 1992. Chemotherapy 38, 358.
          Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
          Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision21-June-2013 JSW
          DescriptionA potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies.
          FormWhite to off-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number18771-50-1
          RTECSUW5798980
          Chemical formulaC₉H₁₆N₂O₆
          Purity≥90% by TLC
          SolubilityH₂O (200 mg/ml)
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
          Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
          Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
          Riva, C., et al. 1992. Chemotherapy 38, 358.
          Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
          Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.