612084 TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem

612084
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      612084-5UG
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          Plastic ampoule 5 μg
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          Description
          OverviewNative TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
          Catalogue Number612084
          Brand Family Calbiochem®
          SynonymsTissue Inhibitor of Metalloproteinase-2
          References
          ReferencesGreene, J., et al. 1996. J. Biol. Chem. 271, 30375.
          Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
          Product Information
          ATP CompetitiveN
          FormLiquid
          FormulationIn 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, pH 7.0.
          ReversibleN
          Applications
          Biological Information
          Primary TargetMMP-1
          Purity≥90% by SDS-PAGE
          SourcePrepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem Certificates of Analysis

          TitleLot Number
          612084

          References

          Reference overview
          Greene, J., et al. 1996. J. Biol. Chem. 271, 30375.
          Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2008 RFH
          SynonymsTissue Inhibitor of Metalloproteinase-2
          DescriptionNative TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
          FormLiquid
          FormulationIn 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, pH 7.0.
          SourcePrepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Purity≥90% by SDS-PAGE
          Storage ≤ -70°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Toxicity Standard Handling
          ReferencesGreene, J., et al. 1996. J. Biol. Chem. 271, 30375.
          Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.