505626 | (S)-Sulpiride - CAS 23672-07-3 - Calbiochem

505626
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₅H₂₃N₃O₄S 23672-07-3

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05626.0001
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          Glass bottle 100 mg
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          Description
          OverviewDopamine D2 receptor antagonist with good aqueous solubility. S-sulpiride (200 nm) was used to confirm that dopamine currents were mediated through the D2 receptor in whole animal rat brain preps. IC50 of 0.01012 µM Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis.
          Catalogue Number505626
          Brand Family Calbiochem®
          Synonyms(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride
          References
          ReferencesEagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
          Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
          Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.
          Product Information
          CAS number23672-07-3
          FormWhite solid
          Hill FormulaC₁₅H₂₃N₃O₄S
          Chemical formulaC₁₅H₂₃N₃O₄S
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetD2-like dopamine receptors
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Eagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
          Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
          Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          Synonyms(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride
          DescriptionDopamine D2 receptor antagonist with good aqueous solubility. S-sulpiride (200 nm) was used to confirm that dopamine currents were mediated through the D2 receptor in whole animal rat brain preps. IC50 of 0.01012 µM Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis.
          FormWhite solid
          CAS number23672-07-3
          Chemical formulaC₁₅H₂₃N₃O₄S
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesEagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
          Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
          Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.