472804 | S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem

472804
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₇H₁₅N₃O₂S · 2HCl 209589-59-3

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      472804-10MG
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          Plastic ampoule 10 mg
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          Description
          OverviewA cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).
          Catalogue Number472804
          Brand Family Calbiochem®
          SynonymsNδ-(S-Methyl)isothioureido-L-ornithine
          References
          ReferencesKrishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
          Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
          Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.
          Product Information
          CAS number209589-59-3
          ATP CompetitiveN
          FormWhite to off-white solid
          Hill FormulaC₇H₁₅N₃O₂S · 2HCl
          Chemical formulaC₇H₁₅N₃O₂S · 2HCl
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetRat neuronal nitric oxide synthase
          Primary Target IC<sub>50</sub>300 nM for rat neuronal nitric oxide synthase
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          472804

          References

          Reference overview
          Krishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
          Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
          Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.

          Brochure

          Title
          Nitric Oxide and Oxidative Stress Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-January-2017 JSW
          SynonymsNδ-(S-Methyl)isothioureido-L-ornithine
          DescriptionA cell-permeable, inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).
          FormWhite to off-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number209589-59-3
          Chemical formulaC₇H₁₅N₃O₂S · 2HCl
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityH₂O (50 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Toxicity Standard Handling
          ReferencesKrishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
          Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
          Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.