504395 | (RS)-PPG - CAS 120667-15-4 - Calbiochem

504395
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₁₀NO₅P 120667-15-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04395.0001
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          Glass bottle 5 mg
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          Description
          OverviewA potent and subtype-selective agonist for group III metabotropic glutamate receptors. 25-fold higher selectivity for mGlu8 (EC50 =0.21 µM ) than for other group III mGlu receptors (EC50 = 5.2, 4.7, and 185 µM for mGlu4,6,7, respectively). Widely used as anticonvulsant, antidepressant, anxiolytic, and neuroprotective agent in research.
          Catalogue Number504395
          Brand Family Calbiochem®
          Synonyms(RS)-4-Phosphonophenylglycine
          References
          ReferencesGasparini, F., et al. 1999. J. Pharmacol. Exp. Ther. 289, 1678.
          Palucha, A., et al. 2004. Neuropharmacology. 46, 151.
          Bigge, C., et al. 1989. J. Med. Chem. 32, 1580.
          Schoepp, D., et al. 1999. Neuropharmacology. 38, 1431.
          Product Information
          CAS number120667-15-4
          FormWhite powder
          Hill FormulaC₈H₁₀NO₅P
          Chemical formulaC₈H₁₀NO₅P
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetmGlu₈
          Purity≥97% by NMR
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Gasparini, F., et al. 1999. J. Pharmacol. Exp. Ther. 289, 1678.
          Palucha, A., et al. 2004. Neuropharmacology. 46, 151.
          Bigge, C., et al. 1989. J. Med. Chem. 32, 1580.
          Schoepp, D., et al. 1999. Neuropharmacology. 38, 1431.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-June-2013 JSW
          Synonyms(RS)-4-Phosphonophenylglycine
          DescriptionA potent and subtype-selective agonist for group III metabotropic glutamate receptors. 25-fold higher selectivity for mGlu8 (EC50 =0.21 µM ) than for other group III mGlu receptors (EC50 = 5.2, 4.7, and 185 µM for mGlu4,6,7, respectively). Widely used as anticonvulsant, antidepressant, anxiolytic, and neuroprotective agent in research.
          FormWhite powder
          CAS number120667-15-4
          Chemical formulaC₈H₁₀NO₅P
          Structure formulaStructure formula
          Purity≥97% by NMR
          SolubilityDMSO (2 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesGasparini, F., et al. 1999. J. Pharmacol. Exp. Ther. 289, 1678.
          Palucha, A., et al. 2004. Neuropharmacology. 46, 151.
          Bigge, C., et al. 1989. J. Med. Chem. 32, 1580.
          Schoepp, D., et al. 1999. Neuropharmacology. 38, 1431.