504631 | Quisqualic acid - CAS 52809-07-1 - Calbiochem

504631
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₅H₇N₃O₅ 52809-07-1

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04631.0001
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          Glass bottle 1 mg
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          Description
          OverviewA potent agonist highly selective for group I (EC50 ≤3 µM) over group II and III mGlu receptors (EC50 >40 µM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.
          Catalogue Number504631
          Brand Family Calbiochem®
          Synonymsβ-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
          References
          ReferencesJin, R., et al. 2012. Biochemistry. 41, 15635.
          Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
          Zhang, W., et al. 2006. Biophysical J. 91, 1336.
          Muir, J., et al. 1993. Behav. Brain Res. 57, 123.
          Product Information
          CAS number52809-07-1
          FormWhite powder
          Hill FormulaC₅H₇N₃O₅
          Chemical formulaC₅H₇N₃O₅
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Target Group II and III mGlu receptors
          Purity≥98% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Jin, R., et al. 2012. Biochemistry. 41, 15635.
          Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
          Zhang, W., et al. 2006. Biophysical J. 91, 1336.
          Muir, J., et al. 1993. Behav. Brain Res. 57, 123.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-June-2013 JSW
          Synonymsβ-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
          DescriptionA potent agonist highly selective for group I (EC50 ≤3 µM) over group II and III mGlu receptors (EC50 >40 µM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.
          FormWhite powder
          CAS number52809-07-1
          Chemical formulaC₅H₇N₃O₅
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityH₂O (0.5 mg/ml), 1M NH₄OH (20 mg/ml) or 0.1M HCl (1.4 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesJin, R., et al. 2012. Biochemistry. 41, 15635.
          Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
          Zhang, W., et al. 2006. Biophysical J. 91, 1336.
          Muir, J., et al. 1993. Behav. Brain Res. 57, 123.