538925 Prostaglandin I₂, Sodium Salt - CAS 61849-14-7 - Calbiochem

538925
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₃₁O₅ · Na 61849-14-7

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      538925-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewPotent vasodilatory prostaglandin produced by the endothelium. Induces vasodilation, stimulates cAMP formation. Exhibits cytoprotective and fibrinolytic properties.
          Catalogue Number538925
          Brand Family Calbiochem®
          SynonymsPGI₂, Prostacyclin
          References
          ReferencesVane, J.R. 1985. Adv. Prostaglandin Thromboxane Leukotriene Res. 15, 11.
          Moncada, S., et al. 1979. Pharmacol. Rev. 30, 293.
          Cho, M.J. and Allen, M.A. 1978. Prostaglandins 15, 943.
          Tateson, J.E., et al. 1977. Prostaglandins 13, 389.
          Product Information
          CAS number61849-14-7
          ATP CompetitiveN
          FormCrystalline solid
          Hill FormulaC₂₀H₃₁O₅ · Na
          Chemical formulaC₂₀H₃₁O₅ · Na
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetInduces vasodilation
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 22-36

          Do not breathe dust.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Harmful
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). This product is rapidly hydrolyzed in acidic solutions. The half-life at pH 7.48 is between 3.5 min and 10.5 min at 25°C. At pH 12 the half-life is ~6 days at 25°C. No loss of biological activity was observed at pH 9.37 for 48 h, when stored at 0°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Prostaglandin I₂, Sodium Salt - CAS 61849-14-7 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Prostaglandin I₂, Sodium Salt - CAS 61849-14-7 - Calbiochem Certificates of Analysis

          TitleLot Number
          538925

          References

          Reference overview
          Vane, J.R. 1985. Adv. Prostaglandin Thromboxane Leukotriene Res. 15, 11.
          Moncada, S., et al. 1979. Pharmacol. Rev. 30, 293.
          Cho, M.J. and Allen, M.A. 1978. Prostaglandins 15, 943.
          Tateson, J.E., et al. 1977. Prostaglandins 13, 389.

          Brochure

          Title
          Bioactive Lipids Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision03-November-2009 JSW
          SynonymsPGI₂, Prostacyclin
          DescriptionPotent vasodilatory prostaglandin produced by the endothelium. Induces vasodilation, stimulates cAMP formation. Cytoprotective and fibrinolytic. Inhibits platelet aggregation by receptor mediated stimulation of adenylate cyclase.
          FormCrystalline solid
          CAS number61849-14-7
          Chemical formulaC₂₀H₃₁O₅ · Na
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). This product is rapidly hydrolyzed in acidic solutions. The half-life at pH 7.48 is between 3.5 min and 10.5 min at 25°C. At pH 12 the half-life is ~6 days at 25°C. No loss of biological activity was observed at pH 9.37 for 48 h, when stored at 0°C.
          Toxicity Harmful
          ReferencesVane, J.R. 1985. Adv. Prostaglandin Thromboxane Leukotriene Res. 15, 11.
          Moncada, S., et al. 1979. Pharmacol. Rev. 30, 293.
          Cho, M.J. and Allen, M.A. 1978. Prostaglandins 15, 943.
          Tateson, J.E., et al. 1977. Prostaglandins 13, 389.