420413 | Polymyxin B Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 1405-20-5 - Calbiochem

420413
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #
      1405-20-5

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      420413-20ML
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          Plastic ampoule 20 ml
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          Description
          OverviewAn antibiotic that inhibits phospholipid sensitive Ca2+-dependent protein kinase. Mixture of polymyxin B1 sulfate and polymyxin B2 sulfate. Binds to cell wall and makes it more permeable, causing fluid uptake. Effective against Gram-negative bacteria.
          Catalogue Number420413
          Brand Family Calbiochem®
          SynonymsAerosporin, Sterile-Filtered Aqueous Solution, Cell Culture Tested
          References
          ReferencesLucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
          Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
          Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
          Strasser, R.H., et al. 1992. Circ. Res. 70, 1304.
          Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
          Inaba, H. and Finkins, J.P. 1991. Am. J. Physiol. 261, R26.
          Marra, M.N., et al. 1990. J. Immunol. 144, 662.
          Product Information
          CAS number1405-20-5
          FormClear liquid
          FormulationSupplied at 50 mg/ml in H₂O.
          Applications
          Biological Information
          Biological activity≥7500 units/mg
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSTR1150000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Harmful
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          420413

          References

          Reference overview
          Lucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
          Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
          Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
          Strasser, R.H., et al. 1992. Circ. Res. 70, 1304.
          Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
          Inaba, H. and Finkins, J.P. 1991. Am. J. Physiol. 261, R26.
          Marra, M.N., et al. 1990. J. Immunol. 144, 662.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-July-2008 RFH
          SynonymsAerosporin, Sterile-Filtered Aqueous Solution, Cell Culture Tested
          DescriptionAn antibiotic that inhibits phospholipid sensitive Ca2+-dependent protein kinase. Mixture of polymyxin B1 sulfate and polymyxin B2 sulfate. Binds to cell wall and makes it more permeable, causing fluid uptake. Effective against Gram-negative bacteria.
          FormClear liquid
          FormulationSupplied at 50 mg/ml in H₂O.
          CAS number1405-20-5
          RTECSTR1150000
          Biological activity≥7500 units/mg
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Harmful
          ReferencesLucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
          Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
          Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
          Strasser, R.H., et al. 1992. Circ. Res. 70, 1304.
          Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
          Inaba, H. and Finkins, J.P. 1991. Am. J. Physiol. 261, R26.
          Marra, M.N., et al. 1990. J. Immunol. 144, 662.