311203 NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 65005-57-4 - Calbiochem

311203
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₁₈N₄O₂ . 2HCl 65005-57-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      311203-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewA cell-permeable, reversible inhibitor of nitric oxide synthase in vitro (IC50 = 2-3 µM) and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
          Catalogue Number311203
          Brand Family Calbiochem®
          SynonymsADMA, 2HCl
          References
          ReferencesCloss, E.I., et al. 1997. Nitric Oxide 1, 65.
          Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
          Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
          Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
          Vallance, P., et al. 1992. Lancet 339, 572.
          Product Information
          CAS number65005-57-4
          ATP CompetitiveN
          FormWhite amorphous solid
          Hill FormulaC₈H₁₈N₄O₂ . 2HCl
          Chemical formulaC₈H₁₈N₄O₂ . 2HCl
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetNOS in vitro
          Primary Target IC<sub>50</sub>2-3 µM inhibiting nitric oxide synthase in vitro
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          311203

          References

          Reference overview
          Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
          Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
          Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
          Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
          Vallance, P., et al. 1992. Lancet 339, 572.

          Brochure

          Title
          Nitric Oxide and Oxidative Stress Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision19-June-2008 RFH
          SynonymsADMA, 2HCl
          DescriptionEndogenous reversible inhibitor of nitric oxide synthesis in vitro and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
          FormWhite amorphous solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number65005-57-4
          Chemical formulaC₈H₁₈N₄O₂ . 2HCl
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityH₂O (50 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
          Toxicity Standard Handling
          ReferencesCloss, E.I., et al. 1997. Nitric Oxide 1, 65.
          Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
          Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
          Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
          Vallance, P., et al. 1992. Lancet 339, 572.