481486 | NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem

481486
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₁₂₃H₂₁₅N₃₃O₃₀S

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      481486-500UG
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          Plastic ampoule 500 μg
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          Description
          OverviewAn inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys363 and Gly for Arg364 in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.
          Catalogue Number481486
          Brand Family Calbiochem®
          Synonyms(AAVALLPAVLLALLAPVQRNGQKLMP)
          References
          ReferencesLin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
          Product Information
          ATP CompetitiveN
          DeclarationSold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₂₃H₂₁₅N₃₃O₃₀S
          Chemical formulaC₁₂₃H₂₁₅N₃₃O₃₀S
          Hygroscopic Hygroscopic
          ReversibleN
          Sold on the basis of peptide contentY
          Applications
          Biological Information
          Primary Targetan inactive control for SN50 peptide
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          481486

          References

          Reference overview
          Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision03-March-2008 JSW
          Synonyms(AAVALLPAVLLALLAPVQRNGQKLMP)
          DescriptionAn inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys363 for Asn and Arg364 for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Chemical formulaC₁₂₃H₂₁₅N₃₃O₃₀S
          Peptide SequenceH-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH
          Purity≥97% by HPLC
          SolubilityH₂O (5 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.
          Toxicity Standard Handling
          ReferencesLin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.