454575 N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem

454575
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₅H₉NO₄•H₂O 6384-92-5

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      454575-100MG
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          Plastic ampoule 100 mg
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          Description
          OverviewExcitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
          Catalogue Number454575
          Brand Family Calbiochem®
          SynonymsNMDA
          References
          ReferencesMattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
          Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
          Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.
          Product Information
          CAS number6384-92-5
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₅H₉NO₄•H₂O
          Chemical formulaC₅H₉NO₄•H₂O
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetGlutamate receptor that regulates Ca2+ channels
          Purity>95% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSCI9457000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          454575

          References

          Reference overview
          Mattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
          Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
          Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.

          Brochure

          Title
          Excitotoxic Glutamate Analogs Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-August-2007 JSW
          SynonymsNMDA
          DescriptionAn excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
          FormWhite solid
          CAS number6384-92-5
          RTECSCI9457000
          Chemical formulaC₅H₉NO₄•H₂O
          Structure formulaStructure formula
          Purity>95% by TLC
          SolubilityH₂O (1 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
          Toxicity Standard Handling
          Merck USA index14, 6662
          ReferencesMattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
          Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
          Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.