509886 | Myristoylated Myr-KFEEERARAKWDT, mP13 - Calbiochem

509886
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₈₇H₁₃₈N₂₂O₂₄

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.09886.0001
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          Glass bottle 10 mg
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          Description
          OverviewA cell-permeable, myristoylated 13-mer peptide derived from EXE-motif-containing integrin β3 subunit that inhibits talin association with β3. Shown to inhibit both inside-out and outside-in signaling. Blocks all phases of integrin signaling including fibrinogen binding, platelet adhesion, and clot retraction.

          Please note that the molecular weight for this compound is batch-specific due to variable water content.
          Catalogue Number509886
          Brand Family Calbiochem®
          SynonymsIntegrin Signaling inhibitor II, mP13
          References
          ReferencesShen, B., et al. 2013. Nature 503, 131.
          Product Information
          FormWhite powder
          Hill FormulaC₈₇H₁₃₈N₂₂O₂₄
          Chemical formulaC₈₇H₁₃₈N₂₂O₂₄
          Hygroscopic Hygroscopic
          ReversibleY
          Applications
          Biological Information
          Primary TargetIntegrin alphaIIbbeta3
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceKFEEERARAKWDT
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage ≤ -70°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Shen, B., et al. 2013. Nature 503, 131.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-May-2014 JSW
          SynonymsIntegrin Signaling inhibitor II, mP13
          DescriptionA cell-permeable, myristoylated 13-mer peptide derived from EXE-motif-containing integrin β3 subunit that inhibits talin association with β3. Shown to inhibit both inside-out and outside-in signaling. Blocks all phases of integrin signaling including fibrinogen binding, platelet adhesion, and clot retraction.
          FormWhite powder
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₈₇H₁₃₈N₂₂O₂₄
          Peptide SequenceKFEEERARAKWDT
          Purity≥98% by HPLC
          SolubilityDMSO (100 mg/ml). Not water soluble.
          Storage ≤ -70°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesShen, B., et al. 2013. Nature 503, 131.