506044 Muscimol - CAS 2763-96-4 - Calbiochem

506044
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄H₆N₂O₂ 2763-96-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.06044.0001
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          Glass bottle 1 mg
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          Description
          OverviewA constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
          Catalogue Number506044
          Brand Family Calbiochem®
          SynonymsGABAA Receptor Agonist, Muscimol
          References
          ReferencesChandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
          Fischer, H., et al. 2005. J. Physiol. 564, 465.
          Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.
          Product Information
          CAS number2763-96-4
          FormWhite solid
          Hill FormulaC₄H₆N₂O₂
          Chemical formulaC₄H₆N₂O₂
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetGABAA
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 28

          Very toxic if swallowed.
          S PhraseS: 46

          If swallowed, seek medical advice immediately and show this container or label.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Chandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
          Fischer, H., et al. 2005. J. Physiol. 564, 465.
          Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          SynonymsGABAA Receptor Agonist, Muscimol
          DescriptionA constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
          FormWhite solid
          CAS number2763-96-4
          Chemical formulaC₄H₆N₂O₂
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityH₂O (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Toxic
          ReferencesChandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
          Fischer, H., et al. 2005. J. Physiol. 564, 465.
          Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.