475895 | Monensin, Sodium Salt, High Purity - CAS 22373-78-0 - Calbiochem

475895
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃₆H₆₁O₁₁ . Na 22373-78-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      475895-250MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Alu drum 250 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewPolyether antibiotic that functions as a Na+ ionophore by forming stable complexes with monovalent cations that are able to cross the plasma membrane. Blocks glycoprotein secretion. Inhibits the ability of HDL to decrease cellular cholesterol esterification. Also reported to induce catecholamine secretion from adrenal chromaffin cells.
          Catalogue Number475895
          Brand Family Calbiochem®
          References
          ReferencesInabayashi, M., et al. 1995. Biochemistry 34, 3455.
          Mendez, A.J. 1995. J. Biol. Chem. 270, 5891.
          Sakuragawa, N., et al. 1994. Biochim. Biophys. Acta 1213, 193.
          Griffin, T., et al. 1993. J. Natl. Cancer Inst. 85, 292.
          Rushfeldt, C., and Smedsrtod, B. 1993. Cancer Res. 53, 658.
          Hoya, A., and Venosa, R.A. 1992. Biochem. Biophys. Acta 1104, 123.
          Kok, J.W. 1992. J. Cell. Sci. 103, 1139.
          Takemura, H., and Ohshika, H. 1992. Biochem. Pharmacol. 44, 1395.
          Product Information
          CAS number22373-78-0
          ATP CompetitiveN
          FormOff-white to beige solid
          Hill FormulaC₃₆H₆₁O₁₁ . Na
          Chemical formulaC₃₆H₆₁O₁₁ . Na
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetFunctions as a Na+ ionophore
          Purity≥97% by Assay
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSJH2830000
          Safety Information
          R PhraseR: 26/27/28

          Very toxic by inhalation, in contact with skin and if swallowed.
          S PhraseS: 22-36/37/39-45

          Do not breathe dust.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C. Unstable in acidic solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          475895

          References

          Reference overview
          Inabayashi, M., et al. 1995. Biochemistry 34, 3455.
          Mendez, A.J. 1995. J. Biol. Chem. 270, 5891.
          Sakuragawa, N., et al. 1994. Biochim. Biophys. Acta 1213, 193.
          Griffin, T., et al. 1993. J. Natl. Cancer Inst. 85, 292.
          Rushfeldt, C., and Smedsrtod, B. 1993. Cancer Res. 53, 658.
          Hoya, A., and Venosa, R.A. 1992. Biochem. Biophys. Acta 1104, 123.
          Kok, J.W. 1992. J. Cell. Sci. 103, 1139.
          Takemura, H., and Ohshika, H. 1992. Biochem. Pharmacol. 44, 1395.

          Brochure

          Title
          Ionophores Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision25-January-2011 JSW
          DescriptionPolyether antibiotic that functions as a Na+ ionophore by forming stable complexes with monovalent cations that are able to cross the plasma membrane. Blocks glycoprotein secretion. Inhibits the ability of HDL to decrease cellular cholesterol esterification. Also reported to induce catecholamine secretion from adrenal chromaffin cells.
          FormOff-white to beige solid
          CAS number22373-78-0
          RTECSJH2830000
          Chemical formulaC₃₆H₆₁O₁₁ . Na
          Structure formulaStructure formula
          Purity≥97% by Assay
          SolubilityChloroform, Ethanol, or Methanol
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C. Unstable in acidic solutions.
          Toxicity Highly Toxic
          Merck USA index14, 6246
          ReferencesInabayashi, M., et al. 1995. Biochemistry 34, 3455.
          Mendez, A.J. 1995. J. Biol. Chem. 270, 5891.
          Sakuragawa, N., et al. 1994. Biochim. Biophys. Acta 1213, 193.
          Griffin, T., et al. 1993. J. Natl. Cancer Inst. 85, 292.
          Rushfeldt, C., and Smedsrtod, B. 1993. Cancer Res. 53, 658.
          Hoya, A., and Venosa, R.A. 1992. Biochem. Biophys. Acta 1104, 123.
          Kok, J.W. 1992. J. Cell. Sci. 103, 1139.
          Takemura, H., and Ohshika, H. 1992. Biochem. Pharmacol. 44, 1395.

          Related Products & Applications

          Alternative Products

          Catalog Number Description  
          475897 Monensin Methyl Ester - Calbiochem Show Pricing & Availability

          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores