444228 | MMP-7 Substrate, Fluorogenic - Calbiochem

444228
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      444228-1MG
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      Stocked 
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          Plastic ampoule 1 mg
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          Description
          OverviewExcellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1 s-1). The cleavage occurs at the Ala-Leu bond.
          Catalogue Number444228
          Brand Family Calbiochem®
          SynonymsMatrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
          References
          ReferencesWelch, A.R., et al. 1996. Biochemistry 35, 10103.
          Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.
          Product Information
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₅₂H₇₇N₁₇O₁₄
          Chemical formulaC₅₂H₇₇N₁₇O₁₄
          ReversibleN
          Applications
          Biological Information
          Primary TargetFluorogenic substrate for MMP-7
          Primary Target IC<sub>50</sub>kcat/Km = 1.9 x 105 M⁻¹ s⁻¹for MMP-7
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceDNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          444228

          References

          Reference overview
          Welch, A.R., et al. 1996. Biochemistry 35, 10103.
          Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-August-2008 RFH
          SynonymsMatrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
          DescriptionExcellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1s-1). Excitation maximum: ~280 nm; emission maximum: ~360 nm. The cleavage occurs at the Ala-Leu bond.
          FormYellow solid
          Chemical formulaC₅₂H₇₇N₁₇O₁₄
          Peptide SequenceDNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
          Purity≥90% by HPLC
          Solubility10% Acetic acid (1 mg/ml)
          Storage -20°C
          Protect from moisture
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesWelch, A.R., et al. 1996. Biochemistry 35, 10103.
          Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.

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          Categories

          Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Protease Substrates