427572 | Lactosyl Ceramide, Bovine - CAS 4682-48-8 - Calbiochem

427572
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₅₃H₁₀₁NO₁₃ 4682-48-8

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      427572-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewA neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.
          M.W. 960.4 (based on tricosanoyl - 23:0).
          Catalogue Number427572
          Brand Family Calbiochem®
          SynonymsLC, Galβ,1,4Glc-Cer, LacCer
          References
          ReferencesBhunia, A.K., et al. 1997. J. Biol. Chem. 272, 15642.
          Bhunia, A.K., et al. 1996. J. Biol. Chem. 271, 10660.
          Zacharias, C., et al. 1994. J. Biol. Chem. 269, 13313.
          Product Information
          CAS number4682-48-8
          ATP CompetitiveN
          FormColorless solid
          Hill FormulaC₅₃H₁₀₁NO₁₃
          Chemical formulaC₅₃H₁₀₁NO₁₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetA neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSFK1000000
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
          Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          427572

          References

          Reference overview
          Bhunia, A.K., et al. 1997. J. Biol. Chem. 272, 15642.
          Bhunia, A.K., et al. 1996. J. Biol. Chem. 271, 10660.
          Zacharias, C., et al. 1994. J. Biol. Chem. 269, 13313.

          Brochure

          Title
          Bioactive Lipids Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision14-September-2007 RFH
          SynonymsLC, Galβ,1,4Glc-Cer, LacCer
          DescriptionA neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fos expression in human aortic smooth muscle cells.

          Molecular weight: 960.4 (based on tricosanyl -23:0)
          FormColorless solid
          CAS number4682-48-8
          RTECSFK1000000
          Chemical formulaC₅₃H₁₀₁NO₁₃
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityEthanol (1 mM) and methanol (1 mM)
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
          Toxicity Irritant
          ReferencesBhunia, A.K., et al. 1997. J. Biol. Chem. 272, 15642.
          Bhunia, A.K., et al. 1996. J. Biol. Chem. 271, 10660.
          Zacharias, C., et al. 1994. J. Biol. Chem. 269, 13313.