105020 L-Leucine

105020
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #EC NumberHill FormulaMolar MassGrade Value
      61-90-5 200-522-0 C₆H₁₃NO₂ 131.18 g/mol Ph Eur,USP

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      1050201000
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          Plastic bottle 1 kg
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          1050209010
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              Plastic drum 10 kg
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              Description
              Catalogue Number105020
              SynonymsLeu
              References
              Product Information
              CAS number61-90-5
              EC number200-522-0
              GradePh Eur,USP
              Hill FormulaC₆H₁₃NO₂
              Molar Mass131.18 g/mol
              HS Code2922 49 85
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Physicochemical Information
              Density1.17 g/cm3 (20 °C)
              Melting Point270 - 340 °C (decomposition)
              pH value5.5 - 6.5 (20 g/l, H₂O, 20 °C)
              Vapor pressure<1 hPa (20 °C)
              Bulk density300 - 400 kg/m3
              Solubility18.9 g/l
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSOH2850000
              Storage class10 - 13 Other liquids and solids
              WGKWGK 1 slightly hazardous to water
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageStore at +5°C to +30°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
              Identity (IR-spectrum)passes test
              Identity (specific rotation)passes test
              Appearancewhite to almost white, crystalline powder or shiny flakes
              Appearance of solution (50 g/l; hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
              Spec. rotation (α 20/D, 40 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+14.5 to +16.5
              Spec. rotation (α 25/D, 40 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+14.9 to +17.3
              pH (10 g/l, CO₂-free water)5.5 - 7.0
              Chloride (Cl)≤ 200 ppm
              Sulfate (SO₄)≤ 300 ppm
              Fe (Iron)≤ 10 ppm
              Related Compounds, total (TLC)≤ 0.5 %
              Related compounds (HPLC) (Isoleucine)≤ 0.8 %
              Related compounds (HPLC) (Any unspecified impurity)≤ 0.2 %
              Related compounds (HPLC) (Total unspecified impurities)≤ 1.0 %
              Ninhydrin-positive substances (LC) (impurity A (570 nm))≤ 0.8 %
              Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
              Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
              Ninhydrin-positive substances (LC) (total impurities)≤ 1.0 %
              Residual solvents (ICH Q3C)excluded by manufacturing process
              Sulfated ash (600 °C)≤ 0.1 %
              Loss on drying (105 °C; 3 h)≤ 0.2 %
              Bacterial endotoxins≤ 3.0 I.U./g
              Microbiological test (total aerobic microbial count (TAMC))≤ 100 CFU/g
              Microbiological test (total yeast and mould count (TYMC))≤ 100 CFU/g
              Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
              Corresponds to Ph. Eur., USP
              Corresponds to Ph. Eur., USP

              Documentation

              Material Qualification Dossier

              Title

              Quality Management Dossier

              Title

              Operational Excellence Dossier

              Title

              L-Leucine SDS

              Title

              Safety Data Sheet (SDS) 

              L-Leucine Certificates of Analysis

              Product Number PackagingSpecificationLot Number
              1050201000 Plastic bottlePDF Specification Document
              1050209010 Plastic drumPDF Specification Document

              Certificates

              Title