407711 | Interleukin-12, Human, Recombinant, S. frugiperda

407711
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407711-5UG
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      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
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      Available
        Remaining : Will advise
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          Contact Customer Service

          Plastic ampoule 5 μg
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          Description
          OverviewRecombinant, human interleukin-12 expressed in S. frugiperda insect cells. Pleiotropic cytokine that is produced by monocytes/macrophages, B cells, and connective tissue-type mast cells. Also known as natural killer cell stimulatory factor and cytotoxic lymphocyte maturation factor. A potent inducer of IFN-γ production and T cell differentiation and function.
          Catalogue Number407711
          Brand Family Calbiochem®
          SynonymsrhIL-12
          References
          ReferencesKang, K., et al. 1996. J. Immunol. 156, 1402.
          Riemann, H., et al. 1996. J. Immunol. 156, 1799.
          Brunda, M.J., et al. 1994. J. Leukoc. Biol. 55, 280.
          Smith, T.J., et al. 1994. Eur. J. Immunol. 24, 822.
          Gubler, U., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4143.
          Stern, A.S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6808.
          Kobayashi, M., et al. 1989. J. Exp. Med. 170, 827.
          Product Information
          FormLyophilized
          FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-12.
          Applications
          Biological Information
          Biological activityED₅₀ = 50-200 pg/ml as measured by its ability to stimulate the proliferation of PHA-activated human lymphoblasts
          Purity≥95% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: ≤1.0 EU/µg IL-12
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          407711

          References

          Reference overview
          Kang, K., et al. 1996. J. Immunol. 156, 1402.
          Riemann, H., et al. 1996. J. Immunol. 156, 1799.
          Brunda, M.J., et al. 1994. J. Leukoc. Biol. 55, 280.
          Smith, T.J., et al. 1994. Eur. J. Immunol. 24, 822.
          Gubler, U., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4143.
          Stern, A.S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6808.
          Kobayashi, M., et al. 1989. J. Exp. Med. 170, 827.

          Brochure

          Title
          Growth Factors and Cytokines Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision23-July-2008 RFH
          SynonymsrhIL-12
          DescriptionRecombinant, human interleukin-12 expressed in S. frugiperda insect cells. Pleiotropic cytokine that is produced by monocytes/macrophages, B-cells, and connective tissue type mast cells. Also known as natural killer cell stimulatory factor and cytotoxic lymphocyte maturation factor. A potent inducer of IFN-γ production and T-cell differentiation and function.
          FormLyophilized
          FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-12.
          Purity≥95% by SDS-PAGE
          ContaminantsEndotoxin: ≤1.0 EU/µg IL-12
          Biological activityED₅₀ = 50-200 pg/ml as measured by its ability to stimulate the proliferation of PHA-activated human lymphoblasts
          SolubilityReconstitute to a concentration ≥1 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Standard Handling
          ReferencesKang, K., et al. 1996. J. Immunol. 156, 1402.
          Riemann, H., et al. 1996. J. Immunol. 156, 1799.
          Brunda, M.J., et al. 1994. J. Leukoc. Biol. 55, 280.
          Smith, T.J., et al. 1994. Eur. J. Immunol. 24, 822.
          Gubler, U., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4143.
          Stern, A.S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6808.
          Kobayashi, M., et al. 1989. J. Exp. Med. 170, 827.