407271 | Integrin αMβ₂ Ligand - CAS 307525-40-2 - Calbiochem

407271
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₉H₁₅NOS₂ 307525-40-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407271-5MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Plastic ampoule 5 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA cell-permeable thioxothiazolidine compound that displays anti-inflammatory properties. Shown to increase cell adhesion and lowers leukemia cell migration in vitro and leukocyte recruitment in vivo and displays anti-inflammatory properties. Binds to and stabilizes integrin αM I domain active conformation and enhances the ligands' (pro-MMP-9 and fibrinogen) binding ability.
          Catalogue Number407271
          Brand Family Calbiochem®
          Synonyms3-(o-Tolyl)-5-(3-phenyl-2-propenylidene)-2-thioxo-1,3-thiazolin-4-one, IMB-10, αMβ2 Agonist I, CD11b Agonist I, CD11b/CD18 Agonist I, CR3 Agonist I, Mac-1 Agonist I
          References
          ReferencesBjorklund, M., et al. 2006. Biochemistry 45, 2862.
          Product Information
          CAS number307525-40-2
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₁₉H₁₅NOS₂
          Chemical formulaC₁₉H₁₅NOS₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetBinds to and stabilizes integrin αM I domain active conformation
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Bjorklund, M., et al. 2006. Biochemistry 45, 2862.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-April-2011 RFH
          Synonyms3-(o-Tolyl)-5-(3-phenyl-2-propenylidene)-2-thioxo-1,3-thiazolin-4-one, IMB-10, αMβ2 Agonist I, CD11b Agonist I, CD11b/CD18 Agonist I, CR3 Agonist I, Mac-1 Agonist I
          DescriptionA cell-permeable thioxothiazolidine compound that displays anti-inflammatory properties. Shown to increase cell adhesion and lowers leukemia cell migration in vitro and leukocyte recruitment in vivo and displays anti-inflammatory properties. Binds to and stabilizes integrin αM I domain active conformation and enhances the ligands' (pro-MMP-9 and fibrinogen) binding ability.
          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number307525-40-2
          Chemical formulaC₁₉H₁₅NOS₂
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (15 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBjorklund, M., et al. 2006. Biochemistry 45, 2862.