200488 | InSolution™Bestatin, Hydrochloride - Calbiochem

200488
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₁₆H₂₄N₂O₄ • HCl

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      200488-10MG
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      Stocked 
      Discontinued
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      Available
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          Glass bottle 10 mg
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          Description
          OverviewA metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
          Catalogue Number200488
          Brand Family Calbiochem®
          Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
          References
          ReferencesMerck Index: 14, 9842.
          Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
          Taylor, A., et al. 1993. Biochemistry 32, 784.
          Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
          Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
          Product Information
          FormLiquid
          FormulationSupplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
          Hill FormulaC₁₆H₂₄N₂O₄ • HCl
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetMetalloproteases
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          200488

          References

          Reference overview
          Merck Index: 14, 9842.
          Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
          Taylor, A., et al. 1993. Biochemistry 32, 784.
          Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
          Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision21-September-2012 JSW
          Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
          DescriptionA metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
          FormLiquid
          FormulationSupplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
          Intert gas (Yes/No) Packaged under inert gas
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Storage -20°C
          Protect from light
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesMerck Index: 14, 9842.
          Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
          Taylor, A., et al. 1993. Biochemistry 32, 784.
          Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
          Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.