530748 InSolution™ SRT1720, HCl - CAS 1001645-58-4 - Calbiochem

530748
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₅H₂₃N₇OS • 4HCl 1001645-58-4

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.30748.0001
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          Glass bottle 10 mg
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          Description
          OverviewAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

          Please note that the molecular weight for this compound is batch-specific due to variable water content.
          Catalogue Number530748
          Brand Family Calbiochem®
          SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
          References
          ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
          Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
          Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
          Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
          Jin, L., et al. 2009. Protein Sci. 18, 514.
          Feige, J.N., et al. 2008. Cell Metab. 8, 347.
          Milne, J.C., et al. 2007. Nature 450, 712.
          Product Information
          CAS number1001645-58-4
          FormLiquid
          FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
          Hill FormulaC₂₅H₂₃N₇OS • 4HCl
          Chemical formulaC₂₅H₂₃N₇OS • 4HCl
          Hygroscopic Hygroscopic
          ReversibleY
          Applications
          Biological Information
          Primary TargetSIRT3
          Secondary targetp300 HAT
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          InSolution™ SRT1720, HCl - CAS 1001645-58-4 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Baur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
          Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
          Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
          Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
          Jin, L., et al. 2009. Protein Sci. 18, 514.
          Feige, J.N., et al. 2008. Cell Metab. 8, 347.
          Milne, J.C., et al. 2007. Nature 450, 712.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-June-2014 JSW
          SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
          DescriptionAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).
          FormLiquid
          FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          CAS number1001645-58-4
          Chemical formulaC₂₅H₂₃N₇OS • 4HCl
          Purity≥98% by HPLC
          Storage ≤ -70°C
          Hygroscopic
          Protect from light
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
          Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
          Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
          Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
          Jin, L., et al. 2009. Protein Sci. 18, 514.
          Feige, J.N., et al. 2008. Cell Metab. 8, 347.
          Milne, J.C., et al. 2007. Nature 450, 712.