540223 InSolution™ Purmorphamine - Calbiochem

540223
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₃₁H₃₂N₆O₂

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      540223-5MG
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      Stocked 
      Discontinued
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          Plastic ampoule 5 mg
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          Description
          Catalogue Number540223
          Brand Family Calbiochem®
          References
          ReferencesWu, X., et al. 2004. Chem. Biol. 11, 1229.
          Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.
          Product Information
          FormLiquid
          FormulationA 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
          Hill FormulaC₃₁H₃₂N₆O₂
          Chemical formulaC₃₁H₃₂N₆O₂
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Applications
          ApplicationInSolution™ Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.
          Biological Information
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/38

          Irritating to eyes and skin.
          S PhraseS: 26-36-45

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Irritant
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          InSolution™ Purmorphamine - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          InSolution™ Purmorphamine - Calbiochem Certificates of Analysis

          TitleLot Number
          540223

          References

          Reference overview
          Wu, X., et al. 2004. Chem. Biol. 11, 1229.
          Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision26-August-2008 JSW
          DescriptionA cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
          FormLiquid
          FormulationA 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₃₁H₃₂N₆O₂
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Irritant
          ReferencesWu, X., et al. 2004. Chem. Biol. 11, 1229.
          Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.