504904 Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem

504904
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₁H₂₇NO₂•0.5C₄H₆O₆ 23210-58-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04904.0001
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          Glass bottle 10 mg
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          Description
          OverviewA partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50 = 0.15 µM, maximal inhibition ˜90%) over other subtypes (IC50 = 39, 29, 76 µM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype NMDA receptors.

          Please note that the molecular weight for this compound is batch-specific due to variable water content.
          Catalogue Number504904
          Brand Family Calbiochem®
          Synonymserythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
          References
          ReferencesZhang, H., et al. 2013. Mol. Brain. 6, 13.
          Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
          Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
          Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
          Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.
          Product Information
          CAS number23210-58-4
          FormWhite solid
          Hill FormulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
          Chemical formulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetGluN1/N2B subtype NMDA receptors
          Primary Target IC<sub>50</sub>0.15 →M
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Zhang, H., et al. 2013. Mol. Brain. 6, 13.
          Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
          Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
          Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
          Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision17-July-2013 JSW
          Synonymserythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
          DescriptionA partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50 = 0.15 µM, maximal inhibition ˜90%) over other subtypes (IC50 = 39, 29, 76 µM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype NMDA receptors.
          FormWhite solid
          CAS number23210-58-4
          Chemical formulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesZhang, H., et al. 2013. Mol. Brain. 6, 13.
          Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
          Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
          Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
          Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.