401483 | IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem

401483
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₂H₁₁N₃O₂S 354811-10-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      401483-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewAn ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
          Catalogue Number401483
          Brand Family Calbiochem®
          Synonyms(5-Phenyl-2-ureido)thiophene-3-carboxamide
          References
          ReferencesBaxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
          Product Information
          CAS number354811-10-2
          ATP CompetitiveY
          FormOff-white solid
          Hill FormulaC₁₂H₁₁N₃O₂S
          Chemical formulaC₁₂H₁₁N₃O₂S
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetIKK-2
          Primary Target IC<sub>50</sub>13 nM
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          401483

          References

          Reference overview
          Baxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-April-2011 RFH
          Synonyms(5-Phenyl-2-ureido)thiophene-3-carboxamide
          DescriptionAn ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
          FormOff-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number354811-10-2
          Chemical formulaC₁₂H₁₁N₃O₂S
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (50 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          ReferencesBaxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.