504483 | Homoquinolinic acid - CAS 490-75-5 - Calbiochem

504483
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₇NO₄ 490-75-5

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04483.0001
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          Glass bottle 10 mg
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          Description
          OverviewA potent agonist for NMDA receptor with subunit-selectivity of NR2A/B (EC50 = 26 µM) over NR2C (EC50 = 60 µM). Used as a potent neurotoxic agent and for identifying endogenous receptors containing the NR2C subunit.
          Catalogue Number504483
          Brand Family Calbiochem®
          Synonyms3-Carboxymethylpyridine-2-carboxylic acid, 3-Pyridineacetic acid, 2-carboxy-Homoquinolinate
          References
          ReferencesOlverman, H., et al, 1988. Neuroscience. 26, 17.
          Prado de Carvalho, I., et al. 1996. Neurochem. Int. 28, 445.
          Stone, T.W. 1984. Br. J. Pharmacol. 81 175.
          Woodhall, G., et al. 2001. J. Neurophysiol. 86 1644.
          Cebere, A., et al. 2003. Neurochem. Res. 28 1193.
          Product Information
          CAS number490-75-5
          FormWhite solid
          Hill FormulaC₈H₇NO₄
          Chemical formulaC₈H₇NO₄
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetNMDA receptors
          Purity≥98% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Olverman, H., et al, 1988. Neuroscience. 26, 17.
          Prado de Carvalho, I., et al. 1996. Neurochem. Int. 28, 445.
          Stone, T.W. 1984. Br. J. Pharmacol. 81 175.
          Woodhall, G., et al. 2001. J. Neurophysiol. 86 1644.
          Cebere, A., et al. 2003. Neurochem. Res. 28 1193.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision26-July-2013 JSW
          Synonyms3-Carboxymethylpyridine-2-carboxylic acid, 3-Pyridineacetic acid, 2-carboxy-Homoquinolinate
          DescriptionA potent agonist for NMDA receptor with subunit-selectivity of NR2A/B (EC50 = 26 µM) over NR2C (EC50 = 60 µM). Used as a potent neurotoxic agent and for identifying endogenous receptors containing the NR2C subunit.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number490-75-5
          Chemical formulaC₈H₇NO₄
          Structure formulaStructure formula
          Purity≥98% by TLC
          Solubility1N NaOH
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesOlverman, H., et al, 1988. Neuroscience. 26, 17.
          Prado de Carvalho, I., et al. 1996. Neurochem. Int. 28, 445.
          Stone, T.W. 1984. Br. J. Pharmacol. 81 175.
          Woodhall, G., et al. 2001. J. Neurophysiol. 86 1644.
          Cebere, A., et al. 2003. Neurochem. Res. 28 1193.