345736 | Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem

345736
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₈₄H₁₄₆N₄O₃₉ · 2NH₄

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      345736-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewUseful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM1 by bacterial and mammalian neuraminidases without detergent or bile salts. Note: the moleculare weight is based on on stearoyl-18:0.
          Catalogue Number345736
          Brand Family Calbiochem®
          SynonymsCer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
          References
          ReferencesLongee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
          Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
          Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
          Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          Hill FormulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
          Chemical formulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetProtein kinase C
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          345736

          References

          Reference overview
          Longee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
          Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
          Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
          Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.

          Brochure

          Title
          Gangliosides Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-September-2007 JSW
          SynonymsCer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
          DescriptionDisialoganglioside prepared from bovine gray matter. Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM1 by bacterial and mammalian sialidases without detergent or bile salts. One mole yields 2 moles of sialic acid by thiobarbituric acid assay. The molecular weight is based on stearoyl-18:0.

          Note: This product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock.
          FormLyophilized
          Chemical formulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityChloroform:Methanol (2:1) or DMSO. For use in aqueous systems, dissolve in a small amount of DMSO and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions may be filter sterilized.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
          Toxicity Irritant
          ReferencesLongee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
          Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
          Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
          Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.