361541 | GSK-3β Inhibitor II - CAS 478482-75-6 - Calbiochem

361541
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₄H₁₀IN₃OS 478482-75-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      361541-5MG
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          Plastic ampoule 5 mg
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          Description
          OverviewA 2-thio-[1,3,4]-oxadiazole-pyridyl derivative that acts as a potent inhibitor of glycogen synthase kinase-3β (IC50 = 390 nM).
          Catalogue Number361541
          Brand Family Calbiochem®
          SynonymsGlycogen Synthase Kinase-3β Inhibitor II, 2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole
          References
          ReferencesNaerum, L., et al. 2002. Bioorg. Med. Chem. Lett. 12, 1525.
          Product Information
          CAS number478482-75-6
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₁₄H₁₀IN₃OS
          Chemical formulaC₁₄H₁₀IN₃OS
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetGsk-3β
          Primary Target IC<sub>50</sub>390 nM against glycogen synthase kinase-3β
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          361541

          References

          Reference overview
          Naerum, L., et al. 2002. Bioorg. Med. Chem. Lett. 12, 1525.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-october-2007 JSW
          SynonymsGlycogen Synthase Kinase-3β Inhibitor II, 2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole
          DescriptionA 2-thio-[1,3,4]-oxadiazole-pyridyl derivative that acts as a potent inhibitor of glycogen synthase kinase-3b (IC50 = 390 nM).

          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number478482-75-6
          Chemical formulaC₁₄H₁₀IN₃OS
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (10 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesNaerum, L., et al. 2002. Bioorg. Med. Chem. Lett. 12, 1525.