341578 | Fibrinogen, Plasminogen-Depleted, Human Plasma

341578
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      341578-500MG
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          Glass bottle 500 mg
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          Description
          OverviewNative fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Contains ≥ 95% clottable proteins.
          Do not disturb until the fibrinogen is completely solubilized.
          Catalogue Number341578
          Brand Family Calbiochem®
          References
          ReferencesWang, H., et al. 1995. J. Infect. Dis. 171, 85.
          Product Information
          CAS number9001-32-5
          FormLyophilized
          FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
          Applications
          ApplicationPlasminogen-Depleted fibrinogen is a native fibrinogen from which plasminogen is depleted using a Lys-agarose column. Contains ≥ 95% clottable proteins.
          Biological Information
          Purityhomogeneous by SDS-PAGE. Clottable proteins: ≥95%
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          341578

          References

          Reference overview
          Wang, H., et al. 1995. J. Infect. Dis. 171, 85.

          Brochure

          Title
          Coagulation Factors Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-September-2007 RFH
          DescriptionNative fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgery trauma, or in cases of myocardial infarction. It is found at decreased levels in cases of liver cirrhosis and serum hepatitis. The plasminogen was depleted using a Lys-agarose column.
          FormLyophilized
          FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          CAS number9001-32-5
          Purityhomogeneous by SDS-PAGE. Clottable proteins: ≥95%
          SolubilityH₂O (25 mg/ml). To prevent clot formation, warm the H₂O and the fibrinogen to 37°C prior to dissolution.
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.
          Toxicity Harmful
          Merck USA index14, 4071
          ReferencesWang, H., et al. 1995. J. Infect. Dis. 171, 85.