341492 | FeTPPS - Calbiochem

341492
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₄₄H₂₈ClFeN₄O₁₂S₄

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      341492-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewA ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
          Catalogue Number341492
          Brand Family Calbiochem®
          Synonyms5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride
          References
          ReferencesImam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157.
          Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.
          Product Information
          ATP CompetitiveN
          FormDark brown solid
          Hill FormulaC₄₄H₂₈ClFeN₄O₁₂S₄
          Chemical formulaC₄₄H₂₈ClFeN₄O₁₂S₄
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetSelective peroxynitrite scavenger
          Primary Target IC<sub>50</sub>EC50 = 5 µM for cytoprotection against peroxynitrite
          Purity≥95% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          341492

          References

          Reference overview
          Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157.
          Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.

          Brochure

          Title
          Nitric Oxide and Oxidative Stress Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-June-2008 RFH
          Synonyms5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride
          DescriptionA ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
          FormDark brown solid
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₄₄H₂₈ClFeN₄O₁₂S₄
          Structure formulaStructure formula
          Purity≥95% by TLC
          SolubilityH₂O
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
          Toxicity Standard Handling
          ReferencesImam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157.
          Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.