344905 | FURA 2/AM - CAS 108964-32-5 - Calbiochem

344905
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      Overview

      Replacement Information

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      344905-1MG
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          Plastic ampoule 1 mg
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          344905-1SET
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              Glass bottle 1 set
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              344905-5MG
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                  Plastic ampoule 5 mg
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                  Description
                  OverviewCell-permeable ester form of FURA 2. Note: 1 set = 10 x 100 µg.
                  PLURONIC® F-127, PROTEIN GRADE® Detergent (Cat. No. 540025, available separately) is a mild, low-toxicity detergent that can aid in the solubilization of FURA 2/AM.
                  Catalogue Number344905
                  Brand Family Calbiochem®
                  Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
                  References
                  ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
                  Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
                  Schwartz, Y., et al. 1992. Endocrinology 131, 772.
                  Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
                  Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
                  Tsien, R.Y. 1980. Biochemistry 19, 2396.
                  Product Information
                  CAS number108964-32-5
                  ATP CompetitiveN
                  FormYellow solid
                  Hill FormulaC₄₄H₄₇N₃O₂₄
                  Chemical formulaC₄₄H₄₇N₃O₂₄
                  ReversibleN
                  Structure formula ImageStructure formula Image
                  Applications
                  Biological Information
                  Primary TargetRatiometric calcium indicator
                  Purity≥95% by HPLC.
                  Physicochemical Information
                  Cell permeableY
                  Emission max.
                  Excitation max.
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Toxicity Standard Handling
                  Storage -20°C
                  Protect from Light Protect from light
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
                  Packaging Information
                  Packaged under inert gas Packaged under inert gas
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Certificates of Analysis

                  TitleLot Number
                  344905

                  References

                  Reference overview
                  Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
                  Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
                  Schwartz, Y., et al. 1992. Endocrinology 131, 772.
                  Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
                  Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
                  Tsien, R.Y. 1980. Biochemistry 19, 2396.

                  Brochure

                  Title
                  Calcium Metabolism and Related Products Brochure
                  Fluorescent Calcium Probes Technical Bulletin
                  Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision27-June-2008 RFH
                  Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
                  DescriptionCell permeant ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30 times greater fluorescence intensity than QUIN 2 (Cat. No. 551826). Can be used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm). Note: 1 set = 10 x 100 µg.
                  FormYellow solid
                  Intert gas (Yes/No) Packaged under inert gas
                  CAS number108964-32-5
                  Chemical formulaC₄₄H₄₇N₃O₂₄
                  Structure formulaStructure formula
                  Purity≥95% by HPLC.
                  SolubilityDMSO (10 mg/ml). Further dilute with aqueous buffers just prior to use.
                  Storage -20°C
                  Protect from light
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
                  Toxicity Standard Handling
                  ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
                  Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
                  Schwartz, Y., et al. 1992. Endocrinology 131, 772.
                  Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
                  Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
                  Tsien, R.Y. 1980. Biochemistry 19, 2396.

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                  Categories

                  Life Science Research > Inhibitors and Biochemicals