505026 DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: AMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX

Primary Target: AMPA
505026
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₂N₄O₆Na₂ 2379-57-9

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05026.0001
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          		 Glass bottle 10 mg
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          Description
          OverviewA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
          Catalogue Number505026
          Brand Family Calbiochem®
          SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
          References
          ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
          Honor, T., et al. 1998. Science. 241, 701.
          Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
          Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
          Product Information
          CAS number2379-57-9
          FormDark brown solid
          Hill FormulaC₈H₂N₄O₆Na₂
          Chemical formulaC₈H₂N₄O₆Na₂
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetAMPA
          Primary Target IC<sub>50</sub>0.19 to 1.66 uM
          Secondary targetGluK2
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Lee, S., et al. 2010. J. Neurophysiol. 103, 1728.
          Honor, T., et al. 1998. Science. 241, 701.
          Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
          Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision26-July-2013 JSW
          SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
          DescriptionA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
          FormDark brown solid
          CAS number2379-57-9
          Chemical formulaC₈H₂N₄O₆Na₂
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityH₂O (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
          Honor, T., et al. 1998. Science. 241, 701.
          Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
          Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.