204910 | Complement C9, Human

204910
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      204910-250UG
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          Plastic ampoule 250 μg
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          Description
          OverviewNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
          Catalogue Number204910
          Brand Family Calbiochem®
          References
          ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
          Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
          Product Information
          CAS number80295-59-6
          FormLiquid
          FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
          Applications
          Biological Information
          Purity≥95% by SDS-PAGE
          SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Specific Activity≥150,000 C9H50 units/mg
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          204910

          References

          Reference overview
          Stanley, K.K., et al. 1985. EMBO J. 4, 375.
          Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-May-2008 RFH
          DescriptionNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
          FormLiquid
          FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
          Concentration Label Please refer to vial label for lot-specific concentration
          SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          CAS number80295-59-6
          Purity≥95% by SDS-PAGE
          ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
          Specific activity≥150,000 C9H50 units/mg
          Storage ≤ -70°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Toxicity Standard Handling
          ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
          Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.