216100 | Carboplatin - CAS 41575-94-4 - Calbiochem

216100
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₆H₁₂N₂O₄Pt 41575-94-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      216100-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewAn analog of Cisplatin (Cat. No. 232120) with reduced nephrotoxicity. Displays potent antitumor activity.

          Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
          Catalogue Number216100
          Brand Family Calbiochem®
          Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
          References
          ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
          Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
          Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
          Product Information
          CAS number41575-94-4
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₆H₁₂N₂O₄Pt
          Chemical formulaC₆H₁₂N₂O₄Pt
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPotent antitumor activity
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSTP2300000
          Safety Information
          R PhraseR: 20/21/22-42/43-46-61

          Harmful by inhalation, in contact with skin and if swallowed.
          May cause sensitization by inhalation and skin contact.
          May cause heritable genetic damage.
          May cause harm to the unborn child.
          S PhraseS: 22-26-36/37/39-45-53

          Do not breathe dust.
          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Avoid exposure - obtain special instructions before use.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          216100

          References

          Reference overview
          Hall, M.D., et al. 2014. Cancer Res. In press.
          Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
          Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision08-July-2014 JSW
          Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
          DescriptionAn analog of cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.

          Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
          FormWhite solid
          CAS number41575-94-4
          RTECSTP2300000
          Chemical formulaC₆H₁₂N₂O₄Pt
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O with 5% Glucose (10 mg/mL)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful & Carcinogenic / Teratogenic
          Merck USA index14, 1822
          ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
          Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
          Harland, S.J., et al. 1984. Cancer Res. 44, 1693.