504842 CGP 37849 - CAS 127910-31-0 - Calbiochem

CGP 37849 - CAS 127910-31-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (E)-(±)-2-Amino-4-methyl-5-phosphono­-3-pentenoic acid

Primary Target: NMDA receptors
504842
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₆H₁₂NO₅P 127910-31-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04842.0001
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          		 Glass bottle 10 mg
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          Description
          OverviewA highly potent competitive antagonist selective for NMDA receptors (Ki = 35 nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders.
          Catalogue Number504842
          Brand Family Calbiochem®
          Synonyms(E)-(±)-2-Amino-4-methyl-5-phosphono­-3-pentenoic acid
          References
          ReferencesSerafini, G., et al. 2013. Curr. Pharmaceut. Design 19, 1898.
          Szewczyk, B., et al. 2012. Expert. Op. Invest. Drugs 21, 91.
          Przegalinski, E., et al. 2000. Neuropharmacol. 39, 1858.
          Maj, J., et al. 1993. Polish J. Pharmacol. 45, 455.
          Fagg, E., et al. 1990. Br. J. Pharmacol. 99, 791.
          Schmutz, M., et al. 1990. Naunyn-Schmiedebergʹs Arch. Pharmacol. 342, 61.
          Product Information
          CAS number127910-31-0
          FormWhite solid
          Hill FormulaC₆H₁₂NO₅P
          Chemical formulaC₆H₁₂NO₅P
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetNMDA receptors
          Primary Target K<sub>i</sub>35 nM
          Purity≥99% by Chiral HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Serafini, G., et al. 2013. Curr. Pharmaceut. Design 19, 1898.
          Szewczyk, B., et al. 2012. Expert. Op. Invest. Drugs 21, 91.
          Przegalinski, E., et al. 2000. Neuropharmacol. 39, 1858.
          Maj, J., et al. 1993. Polish J. Pharmacol. 45, 455.
          Fagg, E., et al. 1990. Br. J. Pharmacol. 99, 791.
          Schmutz, M., et al. 1990. Naunyn-Schmiedebergʹs Arch. Pharmacol. 342, 61.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision17-July-2013 JSW
          Synonyms(E)-(±)-2-Amino-4-methyl-5-phosphono­-3-pentenoic acid
          DescriptionA highly potent competitive antagonist selective for NMDA receptors (Ki = 35 nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders.
          FormWhite solid
          CAS number127910-31-0
          Chemical formulaC₆H₁₂NO₅P
          Structure formulaStructure formula
          Purity≥99% by Chiral HPLC
          SolubilityH₂O (100 mM). Slight warming is required for complete solubilization.
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSerafini, G., et al. 2013. Curr. Pharmaceut. Design 19, 1898.
          Szewczyk, B., et al. 2012. Expert. Op. Invest. Drugs 21, 91.
          Przegalinski, E., et al. 2000. Neuropharmacol. 39, 1858.
          Maj, J., et al. 1993. Polish J. Pharmacol. 45, 455.
          Fagg, E., et al. 1990. Br. J. Pharmacol. 99, 791.
          Schmutz, M., et al. 1990. Naunyn-Schmiedebergʹs Arch. Pharmacol. 342, 61.