197225 Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem

197225
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₁₅₀H₂₃₄N₄₄O₄₂S

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      197225-1MG
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      Stocked 
      Discontinued
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      Available
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          Plastic ampoule 1 mg
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          Description
          OverviewA cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.
          Catalogue Number197225
          Brand Family Calbiochem®
          Synonymscpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
          References
          ReferencesWang, J-L., et al. 2000. Cancer Res. 60, 1498.
          Product Information
          ATP CompetitiveN
          FormOff-white solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₅₀H₂₃₄N₄₄O₄₂S
          Chemical formulaC₁₅₀H₂₃₄N₄₄O₄₂S
          Hygroscopic Hygroscopic
          ReversibleN
          Applications
          Biological Information
          Primary TargetA negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceCH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          197225

          References

          Reference overview
          Wang, J-L., et al. 2000. Cancer Res. 60, 1498.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-April-2008 RFH
          Synonymscpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
          DescriptionA cell-permeable, mutated cpm-1285 peptide analog where Leu151 is replaced by Ala. Does not induce apoptosis and displays about 15 fold lower Bcl-2 binding. Suitable for use as a negative control.
          FormOff-white solid
          FormulationSupplied as a trifluoroacetate salt.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₁₅₀H₂₃₄N₄₄O₄₂S
          Peptide SequenceCH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
          Purity≥95% by HPLC
          SolubilityDMSO (10 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
          Toxicity Standard Handling
          ReferencesWang, J-L., et al. 2000. Cancer Res. 60, 1498.