178496 Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem

178496
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₇H₂₆O₃ 125316-60-1

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      178496-5MG
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          Plastic ampoule 5 mg
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          Description
          OverviewA cell-permeable retinoid-related molecule that induces tumor growth arrest and apoptosis. The exact molecular basis of the underlying mechanism(s) is not yet well understood, however, studies using ovarian adenocarcinoma cells have shown that CD437/AHPN effectively functions as an ER stress inducer.
          Catalogue Number178496
          Brand Family Calbiochem®
          Synonyms6-(3-(1-Adamantyl)-4-hydroxyphenyl)-2-naphthalene carboxylic acid
          References
          ReferencesWatanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm. 366, 840.
          Holmes, W.F., et al. 2004. J. Cell. Physiol. 199, 317.
          Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci. 10, 44.
          Product Information
          CAS number125316-60-1
          FormOff-white solid
          Hill FormulaC₂₇H₂₆O₃
          Chemical formulaC₂₇H₂₆O₃
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 62-63

          Possible risk of impaired fertility.
          Possible risk of harm to the unborn child.
          S PhraseS: 22-24/25-36/37/39

          Do not breathe dust.
          Avoid contact with skin and eyes.
          Wear suitable protective clothing, gloves and eye/face protection.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          178496

          References

          Reference overview
          Watanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm. 366, 840.
          Holmes, W.F., et al. 2004. J. Cell. Physiol. 199, 317.
          Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci. 10, 44.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision29-February-2008 JSW
          Synonyms6-(3-(1-Adamantyl)-4-hydroxyphenyl)-2-naphthalene carboxylic acid
          DescriptionA cell-permeable retinoid-related molecule that induces tumor growth arrest and apoptosis. The exact molecular basis of the underlying mechanism(s) is not yet well understood, however, studies using ovarian adenocarcinoma cells have shown that CD437/AHPN effectively functions as an ER stress inducer.
          FormOff-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number125316-60-1
          Chemical formulaC₂₇H₂₆O₃
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (39 mg/ml) or Ethanol (39 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          ReferencesWatanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm. 366, 840.
          Holmes, W.F., et al. 2004. J. Cell. Physiol. 199, 317.
          Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci. 10, 44.