ST1681 Anti-SIGIRR Mouse mAb (3H8-2G3)

ST1681
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H M Monoclonal Antibody

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      ST1681-200UL
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          200 ul
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          Description
          OverviewRecognizes the ~32 kDa SIGIRR protein in HepG2 cells.
          Catalogue NumberST1681
          Brand Family Calbiochem®
          SynonymsAnti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain
          References
          Product Information
          FormLiquid
          FormulationUndiluted ascites
          Positive controlHepG2 cells
          PreservativeNone
          Applications
          Key Applications Immunoblotting (Western Blotting)
          Application NotesImmunoblotting (1-5 µg/ml)
          Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
          Biological Information
          ImmunogenFull-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
          Clone3H8-2G3
          HostMouse
          IsotypeIgM
          Species Reactivity
          • Human
          Antibody TypeMonoclonal Antibody
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Regulatory Review
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Anti-SIGIRR Mouse mAb (3H8-2G3) SDS

          Title

          Safety Data Sheet (SDS) 

          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision10-November-2010 RFH
          SynonymsAnti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain
          ApplicationImmunoblotting (1-5 µg/ml)
          DescriptionMouse monoclonal antibody supplied as ascites. Recognizes the ~32 kDa SIGIRR protein.
          BackgroundThe SIGIRR protein acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Its extracellular domain is known to interfere with the heterodimerization of Il1R1 and IL1RAP.
          HostMouse
          ImmunogenFull-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
          Clone3H8-2G3
          IsotypeIgM
          Specieshuman
          Positive controlHepG2 cells
          FormLiquid
          FormulationUndiluted ascites
          PreservativeNone
          CommentsVariables associated with assay conditions will dictate the proper working dilution.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Regulatory Review