434631 | Anti-Lewis x Mouse mAb (P12)

434631
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H M Monoclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      434631-1ML
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          Plastic ampoule 1 ml
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          Description
          OverviewRecognizes the Lewis x carbohydrate chain in normal kidney.
          Catalogue Number434631
          Brand Family Calbiochem®
          SynonymsAnti-Lex
          References
          ReferencesRee, H.J., et al. 1991. Cancer 67, 1338.
          Cordon-Cardo, C., et al. 1986. Int. J. Cancer 37, 667.
          Sakamoto, J., et al. 1986. Cancer Res. 46, 1553
          Sakamoto, J., et al. 1984. Mol. Immunol. 21, 1093.
          Product Information
          FormLiquid
          FormulationTissue Culture Supernatant
          Positive controlNormal kidney tissue
          Preservative≤0.1% sodium azide
          Applications
          Key Applications Paraffin Sections
          Application NotesParaffin Sections (1:10-1:120)
          Application CommentsFor paraffin sections, the recommended working dilution is ≥1:40 (with biotin based detection systems). For fixation, 10% formalin buffered to neutral pH is recommended. Variables associated with assay conditions will dictate the proper working dilutions.
          Biological Information
          Immunogenfresh (non-cultured) human placenta cells
          ImmunogenHuman
          CloneP12
          HostMouse
          IsotypeIgM
          Species Reactivity
          • Human
          Antibody TypeMonoclonal Antibody
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          434631

          References

          Reference overview
          Ree, H.J., et al. 1991. Cancer 67, 1338.
          Cordon-Cardo, C., et al. 1986. Int. J. Cancer 37, 667.
          Sakamoto, J., et al. 1986. Cancer Res. 46, 1553
          Sakamoto, J., et al. 1984. Mol. Immunol. 21, 1093.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-June-2017 JSW
          SynonymsAnti-Lex
          ApplicationParaffin Sections (1:10-1:120)
          DescriptionPurified mouse monoclonal antibody. Recognizes the Lewis x type 2 oligosaccharide chain.
          BackgroundBlood group antigens are a group of molecules formed by sequential addition of saccharides to carbohydrate side chains of lipids and proteins and are detected on erythrocytes, certain epithelial cells and in secretions of some individuals. A, B and H antigens are synthesized by erythrocytes and integrated into their cell membranes. Lewis antigens are not synthesized by erythrocytes but can be absorbed from the plasma onto the surface of red blood cells. Subtle differences in the composition and arrangement of the sugars in the chains are sufficient to generate these distinct specificities. Lewis x is detected in most metastases and invasive cancer cells.
          HostMouse
          Immunogen speciesHuman
          Immunogenfresh (non-cultured) human placenta cells
          CloneP12
          IsotypeIgM
          Specieshuman
          Positive controlNormal kidney tissue
          FormLiquid
          FormulationTissue Culture Supernatant
          Preservative≤0.1% sodium azide
          CommentsFor paraffin sections, the recommended working dilution is ≥1:40 (with biotin based detection systems). For fixation, 10% formalin buffered to neutral pH is recommended. Variables associated with assay conditions will dictate the proper working dilutions.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesRee, H.J., et al. 1991. Cancer 67, 1338.
          Cordon-Cardo, C., et al. 1986. Int. J. Cancer 37, 667.
          Sakamoto, J., et al. 1986. Cancer Res. 46, 1553
          Sakamoto, J., et al. 1984. Mol. Immunol. 21, 1093.

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          Categories

          Life Science Research > Antibodies and Assays > Primary Antibodies