489475 | Anti-LRP-5/6 Mouse mAb (1A12)

489475
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M M Monoclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      489475-50UG
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          Plastic ampoule 50 μg
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          Description
          OverviewRecognizes the ~175 kDa full-length LRP-6 protein and a ~145 kDa proteolytic fragment.
          Catalogue Number489475
          Brand Family Calbiochem®
          SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein-5/6
          References
          ReferencesLi, L., et al. 2001. J. Biol. Chem. 277, 5977.
          Product Information
          FormLiquid
          FormulationIn 150 mM NaCl, 10 mM Tris-glycine, 25% glycerol, 0.5% BSA, pH 7.0.
          Preservative≤0.1% sodium azide
          Applications
          Key Applications Immunoblotting (Western Blotting)
          Application NotesImmunoblotting (1-2 µg/ml)
          Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
          Biological Information
          Immunogena synthetic peptide (DTGTDRIEVTR) corresponding to amino acids 421-431 of the human low density lipoprotein receptor-related protein 6 (LRP-6)
          ImmunogenHuman
          Clone1A12
          HostMouse
          IsotypeIgG2b
          Species Reactivity
          • Human
          • Mouse
          Antibody TypeMonoclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          489475

          References

          Reference overview
          Li, L., et al. 2001. J. Biol. Chem. 277, 5977.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-August-2007 RFH
          SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein-5/6
          ApplicationImmunoblotting (1-2 µg/ml)
          DescriptionPurified mouse monoclonal antibody. Recognizes the ~175 kDa full length LRP-5/6 and the ~145 kDa proteolytic fragment.
          BackgroundLRP-5 and LRP-6 are members of the LDL receptor family involved in the Wnt signaling pathway. The peptide sequence corresponding to amino acid residues 421-431 of the human low density lipoprotein receptor-related protein (LRP) is completely conserved between LRP-5 and LRP-6, as well as between human and mouse.
          HostMouse
          Immunogen speciesHuman
          Immunogena synthetic peptide (DTGTDRIEVTR) corresponding to amino acids 421-431 of the human low density lipoprotein receptor-related protein 6 (LRP-6)
          Clone1A12
          IsotypeIgG2b
          Specieshuman, mouse
          FormLiquid
          FormulationIn 150 mM NaCl, 10 mM Tris-glycine, 25% glycerol, 0.5% BSA, pH 7.0.
          Concentration Label Please refer to vial label for lot-specific concentration
          Preservative≤0.1% sodium azide
          CommentsVariables associated with assay conditions will dictate the proper working dilution.
          Storage ≤ -70°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Toxicity Standard Handling
          ReferencesLi, L., et al. 2001. J. Biol. Chem. 277, 5977.